News Updates
Quality of life changes in patients suffering from knee osteoarthritis treated with bone marrow aspirate concentrate, platelet-rich plasma and hyaluronic acid injections
This study aimed to compare the effects of different treatments on quality of life in knee osteoarthritis patients. It focused on three therapies: bone marrow aspirate concentrate (BMAC), platelet-rich plasma (PRP), and hyaluronic acid (HA).
Mesenchymal Stem Cell Therapy for Superior Gluteal Nerve Injury Post-hip Arthroplasty: A Case Report
This case report describes the use of adipose-derived mesenchymal stem cells (MSCs) to treat an axonal injury of the superior gluteal nerve in a 71-year-old patient. After conventional rehabilitation failed, MSC infiltration was chosen and performed with ultrasound (US) guidance.
Autologous dermal fibroblast injection may decrease rotator cuff retear risk
Autologous dermal fibroblasts may decrease risk of rotator cuff retears after arthroscopic rotator cuff repair vs. repair alone.
Adipose Tissue Bone Graft Performs Well in Initial Test
A novel adipose tissue derived bone graft, tentatively named NVDX3, has performed well in its initial test, a single-arm, open-label first-in-human proof-of-concept study in adults with distal radius fractures.
Bone Marrow Aspirate Concentrate Harvest and Delivery With a Neonatal Nasogastric Tube: A Simple Technique in Hip Arthroscopy
In the past 10 to 15 years, there has been an increasing interest in using orthobiologics to address pathologies of the hip. The use of bone marrow aspirate concentrate (BMAC) showed greater functional improvement in patients with moderate cartilage injuries who had a labral repair than patients without BMAC injection. In hip arthroscopy and preservation, difficulty is encountered during the bone marrow harvest and administration into the hip joint with distraction. Therefore, orthopaedic surgeons need a reliable and reproducible technique to safely administer BMAC in the hip joint to achieve the best results. With this technique, we want to show that BMAC harvest and administration with a neonatal nasogastric feeding tube is easy, safe, and reproducible.
Allogeneic bone marrow derived clonal mesenchymal stromal cells in refractory rheumatoid arthritis: a pilot study
BM-cMSC therapy demonstrated a favorable safety profile and potential efficacy in managing refractory RA. While preliminary results are promising, further studies with larger cohorts and long-term follow-up are needed to validate these findings and optimize therapeutic strategies.
Adipose-derived mesenchymal stem cells combined with platelet-rich plasma are superior options for the treatment of osteoarthritis
There is currently no definitive treatment for osteoarthritis. We examined the therapeutic effects and underlying mechanisms of platelet-rich plasma (PRP) and adipose-derived mesenchymal stem cells (ADSCs), individually or in combination, in a rat model of anterior cruciate ligament-induced degenerative osteoarthritis (OA) of the knee. This study seeks to advance clinical approaches to OA treatment.
