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  • Augmentation with onlay dermal allografts may enhance rotator cuff repair

    Dermal allograft augmentation is commonly indicated for patients with large rotator cuff tears (3 cm to 5 cm), previous unsuccessful rotator cuff repairs or patients with chronic tears with compromised tissue quality and no advanced glenohumeral osteoarthritis (Hamada grades 1 and 2). Prior to the surgical intervention, a crucial step involves the preoperative assessment to ascertain the feasibility of repairing the tear. This assessment involves a comprehensive evaluation of the patient’s MRI scans, focusing on factors such as tear size, tissue quality and the degree of retraction exhibited by the tear.

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  • Stem Cell Therapy May Help Treat Multiple Sclerosis

    A stem cell therapy for multiple sclerosis (MS) appears to be generally safe and effective, but it isn’t widely utilized. Researchers in Sweden are trying to get the word out.

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  • Exploring Stem Cell Therapies in Orthopedics: Are You a Potential Beneficiary?

    The medical world is continuously evolving, with stem cell therapies emerging as a game-changer, especially in orthopedics. The potential to repair, rejuvenate, and reduce inflammation in joints, bones, and surrounding tissues makes this approach a beacon of hope for many. But is it suitable for you?

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  • Stem cell-based therapeutic strategies for rotator cuff tendinopathy

    Stem cell therapy has brought hope for tendon healing in patients with final stage rotator cuff tendinopathy. Some clinical trials have confirmed the effectiveness of stem cell therapy for rotator cuff tendinopathy, but its application has not been promoted and approved. There are still many issues that should be solved prior to using stem cell therapy in clinical applications.

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  • Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing

    Scar formation and loss of cutaneous appendages are the greatest challenges in cutaneous wound healing. Previous studies have indicated that antler reserve mesenchyme (RM) cells and their conditioned medium improved regenerative wound healing with partial recovery of cutaneous appendages.

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  • Aged skeletal stem cells interfere with healing and promote 'inflamm-aging'

    Researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine have discovered how changes in aging skeletal stem cells may be an underlying cause of poor fracture healing, osteoporosis and various blood disorders as well as generalized inflammation and aging (sometimes called "inflamm-aging") of cells and systems throughout the body. However, the researchers are also discovering how they might reinvigorate aging skeletal stem cell so that they start acting younger again, potentially reversing these changes.

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  • Orthobiologics: An Updated Definition

    Source: Scientific Research

    Orthobiologics is a subset of regenerative medicine, which focuses on treating the musculoskeletal system. The main therapeutics utilized include platelet-rich plasma, stem cells, exosomes, and scaffolding matrices. Continuous discoveries and new innovations have led to an increase in both popularity and usage of these therapeutics by various medical and scientific communities.

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  • American Orthopaedic Society for Sports Medicine
  • American Association of Nurse Anesthesiology
  • RYC Orthopedics
  • American Academy of Orthopaedic Surgeons
  • International Society for Hip Arthroscopy
  • Kerlan Jobe Orthopaedic Clinic
  • NYU Langone Medical Center
  • American Board of Orthopaedic Surgery
  • Yale University

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