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Combined arthroscopic rotator cuff repair with mesenchymal stem cell augmentation shows similar functional outcomes but a higher structural integrity rate compared with isolated repair: a meta-analysis of comparative studies

Source: ScienceDirect

Arthroscopic rotator cuff repair (RCR) has guaranteed satisfactory outcomes but remains associated with a significant rate of tendon-bone healing failure. Mesenchymal stem cells (MSCs) have been tested as a promising cell-based therapy for rotator cuff tear (RCT). MSC augmentation has been proposed as a therapy associated with surgical repair, potentially enhancing the overall surgical outcomes for patients with RCTs. The aim of this meta-analysis was to compare functional and structural outcomes between arthroscopic RCR combined with MSC augmentation vs. isolated RCR for RCT.

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  • American Orthopaedic Society for Sports Medicine
  • American Association of Nurse Anesthesiology
  • RYC Orthopedics
  • American Academy of Orthopaedic Surgeons
  • International Society for Hip Arthroscopy
  • Kerlan Jobe Orthopaedic Clinic
  • NYU Langone Medical Center
  • American Board of Orthopaedic Surgery
  • Yale University
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