News Updates
In embryonic stem cells, genes link pluripotency and ease of self-destruction
Source: GEN
Gene networks in human embryonic stem cells (hESCs) have been found to serve two purposes at once. They maintain pluripotency, and they keep apoptosis, or programmed cell death, on a hair trigger. This discovery, from a study led by researchers from Brigham and Women’s Hospital and Harvard Medical School (HMS), suggests that faulty embryonic stem cells have a built-in mechanism to ensure that they are destroyed before they can compromise the functioning of future cells and tissues.
Surgeons explore treatments as elbow injuries increase
Source: Healio
During the past 2 decades, research has shown multiple factors have led to an increase in elbow injuries and surgeries among youth, collegiate and professional overhead-throwing athletes.
Generate looks to in-house stem cell manufacturing
Source: BioPharma Reporter
Generate Life Sciences is establishing a GMP facility in La Jolla, California that it says will enable end-to-end manufacturing of newborn stem cell biologics, bolstering supply and safeguarding clinical research.
Stem Cell Therapy Alleviates Muscular Dystrophy Symptoms in Compassionate-Use Study
Source: GEN
A compassionate-use study has generated promising results for the potential treatment of muscular dystrophies using mesenchymal stem cells (MSCs) derived from Wharton’s jelly (WJ), a substance found in the umbilical cord. The study, led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, and reported in STEM CELLS Translational Medicine, found that individuals treated using WJ-MSC exhibited significant improvement in several body muscles, with no serious side effects.
Safety of Stem Cell Therapy for Chronic Knee Pain Confirmed in New Study
Source: SciTechDaily
A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis. Conducted by a multi-institutional team of researchers in Japan who had developed the new therapy, the study was designed to confirm that their treatment – which involves transplanting the patient’s own mesenchymal stem cells (MSCs) into the affected knee – did not cause tumors.
Stem-cell guidelines: why it was time for an update
Source: Nature
Over the past five years, researchers have kept human embryos alive in culture longer than once thought possible and cultured stem cells into structures that model embryos and organs with unprecedented sophistication.
Severe skin burns now have a new FDA-approved regenerative medicine treatment
Source: MedCity News
Burn patients with the most serious wounds require an autograft: the harvesting of that person’s own healthy skin, which is then transplanted to the burn site. There is now a regenerative medicine alternative. The FDA has approved an engineered skin product that’s placed on the wound, serving as a scaffold for a patient’s skin cells to grow.
