Scar formation and loss of cutaneous appendages are the greatest challenges in cutaneous wound healing. Previous studies have indicated that antler reserve mesenchyme (RM) cells and their conditioned medium improved regenerative wound healing with partial recovery of cutaneous appendages.
Researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine have discovered how changes in aging skeletal stem cells may be an underlying cause of poor fracture healing, osteoporosis and various blood disorders as well as generalized inflammation and aging (sometimes called "inflamm-aging") of cells and systems throughout the body. However, the researchers are also discovering how they might reinvigorate aging skeletal stem cell so that they start acting younger again, potentially reversing these changes.
Source: Scientific Research
Orthobiologics is a subset of regenerative medicine, which focuses on treating the musculoskeletal system. The main therapeutics utilized include platelet-rich plasma, stem cells, exosomes, and scaffolding matrices. Continuous discoveries and new innovations have led to an increase in both popularity and usage of these therapeutics by various medical and scientific communities.
While current approaches involve physiotherapy, anti-inflammatory drugs to delay disease progression, and surgery to limit the impact of the disease, stem cell studies and biologics have shown therapeutic promise. Moreover, recent findings of links between arthritis and other diseases encourage uncovering drug targets to combat arthritis.
Source: Medical Xpress
Two new discoveries led by Cedars-Sinai investigators show stem cell therapies can help accelerate and promote the healing of bone and tendon injuries.
The idea that you already carry your own “fountain of youth” might sound far-fetched at first. However, navigating through the research of how stem cells can benefit human health, that idea becomes much more realistic. Stem cells have the unique ability to develop into different types of cells, making them crucial for the growth and repair of tissues and organs.
Source: Science Daily
A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.