Stem Cell-laden 3D Bioprinting for Osteoarthritis: Orchestrating Chondrogenic Induction and Inflammatory Microenvironment Modulation
Osteoarthritis (OA) involves irreversible cartilage degeneration and requires regenerative strategies due to limited self-repair. This review highlights the potential of stem cell-laden 3D bioprinting to engineer biomimetic cartilage scaffolds with precise control. It analyzes bioprinting methods, bioinks, and cell induction strategies, focusing on the synergistic roles of small molecules, growth factors, and exosomes in guiding stem cell differentiation.
Source: ScienceDirect
