MXenzyme-Reinforced Hydrogel Enhances Stem Cell Therapy Through Multidimensional Regulation in Rheumatoid Arthritis Management
Source: ScienceDirect
Rheumatoid arthritis (RA) is a devastating autoimmune disorder that imposes health and economic burdens on communities worldwide. Although stem cell transplantation has emerged as a promising option for RA management, the osteoimmune microenvironment that characterizes elevated reactive oxygen/nitrogen species (ROS/RNS) and poor oxygen (O2) supply compromise therapeutic efficiency. To address this issue, we present a nanozyme-reinforced hydrogel designed to modulate the immune microenvironment