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Current Status and Future Prospects of Functionalized Mesenchymal Stem Cells for the Treatment of Spinal Cord Injury

Spinal cord injury (SCI) represents a critical neurological disorder characterized by intricate pathophysiological processes. The hostile local environment induced by secondary damage markedly hinders intrinsic neural repair, and currently available therapies exhibit limited clinical effectiveness. Recently, mesenchymal stem cells (MSCs) have attracted considerable attention due to their paracrine-mediated therapeutic properties, including immunoregulatory effects, neurotrophic factor secretion, and promotion of angiogenesis.

Source: ScienceDirect

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