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Comparative Efficacy of Different Doses of Mesenchymal Stem Cells Derived from Different Tissue Sources for Knee Osteoarthritis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Knee osteoarthritis (KOA) remains a leading cause of disability, and mesenchymal stem cells (MSCs) show potential for KOA treatment. However, existing studies demonstrate conflicting results on the optimal dose and tissue source of MSCs for KOA treatment. This gap limits evidence-based treatment decisions.

Source: PubMed Central

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  • American Orthopaedic Society for Sports Medicine
  • American Association of Nurse Anesthesiology
  • RYC Orthopedics
  • American Academy of Orthopaedic Surgeons
  • International Society for Hip Arthroscopy
  • Kerlan Jobe Orthopaedic Clinic
  • NYU Langone Medical Center
  • American Board of Orthopaedic Surgery
  • Yale University
  • OrthoEnglewood