Source: Yale School of Medicine
Collapsed femoral heads caused by osteonecrosis—otherwise known as avascular necrosis— unfortunately represent the root cause for approximately 10% of all hip replacements nationwide. Daniel Wiznia, MD, is utilizing a stem cell treatment at Yale School of Medicine and integrating new techniques along with 3D imaging technology as part of a joint-preservation procedure.
Source: GEN
Gene networks in human embryonic stem cells (hESCs) have been found to serve two purposes at once. They maintain pluripotency, and they keep apoptosis, or programmed cell death, on a hair trigger. This discovery, from a study led by researchers from Brigham and Women’s Hospital and Harvard Medical School (HMS), suggests that faulty embryonic stem cells have a built-in mechanism to ensure that they are destroyed before they can compromise the functioning of future cells and tissues.
Source: Healio
During the past 2 decades, research has shown multiple factors have led to an increase in elbow injuries and surgeries among youth, collegiate and professional overhead-throwing athletes.
Source: BioPharma Reporter
Generate Life Sciences is establishing a GMP facility in La Jolla, California that it says will enable end-to-end manufacturing of newborn stem cell biologics, bolstering supply and safeguarding clinical research.
Source: GEN
A compassionate-use study has generated promising results for the potential treatment of muscular dystrophies using mesenchymal stem cells (MSCs) derived from Wharton’s jelly (WJ), a substance found in the umbilical cord. The study, led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, and reported in STEM CELLS Translational Medicine, found that individuals treated using WJ-MSC exhibited significant improvement in several body muscles, with no serious side effects.
Source: SciTechDaily
A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis. Conducted by a multi-institutional team of researchers in Japan who had developed the new therapy, the study was designed to confirm that their treatment – which involves transplanting the patient’s own mesenchymal stem cells (MSCs) into the affected knee – did not cause tumors.
Source: Nature
Over the past five years, researchers have kept human embryos alive in culture longer than once thought possible and cultured stem cells into structures that model embryos and organs with unprecedented sophistication.