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What are Stem Cells?
A mesenchymal stem cell is a primitive cell with the ability to:
Cell
cell
What are Stem Cells?
A mesenchymal stem cell is a primitive cell with the ability to:
  • Self-Replicate
  • Differentiate into
    multiple tissues
  • Bone
  • Cartilage
  • Muscle
  • Fat
  • Fight Apoptosis
    (Cell Death)
  • Reduce Inflammation

Osteoarthritis

Also called degenerative joint disease, this is the most common type of Arthritis, which occurs most often in older people. This disease affects cartilage, the tissue that cushions and protects the ends of bones in a joint. With osteoarthritis, the cartilage starts to wear away over time. In extreme cases, the cartilage can completely wear away, leaving nothing to protect the bones in a joint, causing bone-on-bone contact. Bones may also bulge, or stick out at the end of a joint, called a bone spur.

Osteoarthritis causes joint pain and can limit a person’s normal range of motion (the ability to freely move and bend a joint). When severe, the joint may lose all movement, causing a person to become disabled. Disability most often happens when the disease affects the spine, Knees, and Hips.

Symptoms

Arthritic symptoms generally include swelling and pain or tenderness in one or more joints for more than two weeks, redness or heat in a joint, limitation of motion of joints, early morning stiffness, and skin changes, including rashes.

Doctors diagnose arthritis with a medical history, physical exam and x-rays of the Hip. There is no blood test for osteoarthritis.

Causes and Risk Factors

Osteoarthritis is caused by the wearing out of the cartilage covering the bone ends in a joint. This may be due to excessive strain over prolonged periods of time, or due to other joint diseases, injury or deformity. Primary osteoarthritis is commonly associated with ageing and general degeneration of joints.

Secondary osteoarthritis is generally the consequence of another disease or condition, such as repeated trauma or surgery to the affected joint, or abnormal joint structures from birth.

Predisposing factors to osteoarthritis of Hip

Some conditions may predispose the Hip to osteoarthritis. It tends to affect people as they get older and particularly affects joints that have to take a lot of stresses and strains.

  • A previous fracture that involved the Hip
  • Growth abnormalities of the Hip (such as a shallow socket) may lead to premature Arthritis
  • Some childhood Hip problems later cause Hip Arthritis (for example, a type of childhood Hip fracture known as a Slipped Epiphysis; also Legg-Perthe’s Disease)
  • Inactive lifestyle- Obesity (overweight) Your weight is the single most important link between diet and Arthritis, as being overweight puts an additional burden on your Hips, Knees, ankles and feet

Predisposing factors to osteoarthritis of knee

Abnormalities of Knee joint function resulting from fractures of the Knee, torn cartilage and torn ligaments can lead to degeneration many years after the injury. The mechanical abnormality leads to excessive wear and tear.

Management of Osteoarthritis

There are several treatments and lifestyle modifications that can help you ease your pain and symptoms.

  • Medications: Pain-relieving medications such as NSAIDs, COX-2 inhibitors and opioids may be prescribed. Topical medications such as ointments can be applied over the skin where there is pain. If the pain is very severe, corticosteroid injection can be given directly into the affected joint to ease the pain.
  • Other Treatments: Your physiotherapist will teach you exercises to keep joints flexible and improve muscle strength. Heat/cold therapy which involves applying heat or cold packs to the joints provides temporary pain relief. Lifestyle modifications can be done to control weight and avoid extra stress on the weight-bearing joints.
  • Surgery: Joint replacement surgery is considered as an option when the pain is so severe that it affects your ability to carry out normal activities.
  • American Academy of Orthopaedic Surgeons
  •  American Orthopaedic Society for Sports Medicine (AOSSM)
  • International Society for Hip Arthroscopy
  • Arthroscopy Association of North America – AANA
  • RYC Orthopaedics
  • Pro Medical New York